Wellnex for Bone and Joints

Osteoarthritis is a degenerative joint disease. It’s caused by progressive destruction of articular cartilage.Joint cartilage mass mostly consists of Collagen and Proteoglycans. The production of cartilage is regulated by specialised cells called Chondrocytes. In the process of ageing Chondrocytes can’t keep up with the natural regeneration process and cartilage starts to break down. Clinical studies indicate that Collagen Peptides stimulates collagen synthesis in Chondrocytes and hence it supports the joint cartilage. The product is gaining wide acceptance across the world as a natural and functional food supplement for joint health without any side effects. Clinical studies recommend that a daily dosage of 10g for three months can be effective and this can be followed by a daily maintenance dose. Being readily soluble in water, it can be mixed with milk, water, juices or any other beverage.

Osteoarthritis (OA) and repetitive, high impact activities, like running, are common cause of joint pain and reduced physical function, and partly caused by cartilage degradation and damage over time.

Cartilage is a tough and flexible connective tissue found covering at the ends of bone joints. It prevents bones from rubbing against each other and acts as a cushion during movements. Cartilage’s collagen proteins and proteoglycans help cartilage maintain its strength .

Cartilage damage and degradation are often caused by aging, obesity, extreme physical work, repetitive high impact activities and injuries. As humans age, our bodies natural ability to produce new collagen declines and new collagen for cartilage is not produced as quickly, leading to joint pain.

Wellnex Collagen Peptide contain two key di-peptides, hydroxyproline-proline, and hydroxyproline-glycine, These diepeptides may help regulate chondrocyte differentiation and play a key role in the maintenance of mature chondrocytes in cartilage. Research suggests that hydroxyproline-proline and its regulatory mechanism explain the therapeutic effect of collagen peptide in improving joint conditions.

One published clinical study revealed that 63% those taking Wellnex Collagen Peptides saw excellent or good improvement after 13 weeks of collagen supplementation, where the placebo group showed the opposite results with 63% reporting no improvement at all. Read the published clinical study.

Wellnex Collagen Peptide supplementation promotes accumulation of collagen peptide in cartilage tissue and its subsequent restructuring, leading to reduced joint pain.

Wellnex Collagen Peptide for Bone Health

Bone is composed of inorganic substances such as hydroxyapatite and organic proteins. Collagen is the main organic protein in bones, making up about 30% of the bone’s composition. It also adds quality, as collagen molecules are the network to which other metals come to settle in order to form the bone structure. The perpetual building and rebuilding of the bones’ structure determines the bone density of each individual. As we age, bone density and strength become important issues to maintaining optimal health. Decreased bone density and deterioration of bone microarchitecture, increase bone fragility and susceptibility to bone fractures. The most common fractures are of the wrist, spine, shoulder and hip. Stimulating the osteoblasts, the cells responsible for bone formulation, to build new bone may help restore bone density loss.

The two key di-peptides found in Wellnex Collagen Peptides, hydroxyproline-proline (Hyp-Pro)and hydroxyproline-glycine (Hyp-Gly) can induce the differentiation of osteoblasts, in theory leading to increased bone density.

In clinical trials, Wellnex Collagen Peptides increased bone density 

• Randomized , Open Label, Multi Center, Two Arms Parrallel Group
• Collagen Peptide (BBCP; Mw5,000)
• Age : 45 – 55 year
• 10g per day dose for 1 year 
• Wellnex = 31 subjects, Comparator – 34 Subjects
• Evaluation : Dexa Bone Scan I Serum BAP I Serum OsteoCalcin

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